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Those with a history of pancreatitis or severe gastrointestinal disease should be particularly careful

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These substances act by disrupting fat cell membranes , causing the cells to break down

Liu P-S, et al

Therefore, iron overload and its induced depletion of Bifidobacterium , along with intestinal dysfunction, form a synergistic effect on the gut-joint axis. By exacerbating local ferroptosis and systemic inflammation, they may synergistically contribute to the pathogenesis and progression of OA

[DOI] [PubMed] [Google Scholar] 22.Borenstein M., Hedges L