During drug shortages, the FDA recognizes that patients may turn to compounded formulations of the medications they need
Zepbound is made by drugmaker Eli Lilly
Gunjal A, Kulkarni A, Bairagi P, Chavan V
The pivotal clinical trials that led to FDA approvalincluding the SUSTAIN trials for diabetes management and the STEP trials for weight managementdid not identify dry mouth as a statistically significant adverse event occurring at notably higher rates in semaglutide-treated patients compared to placebo groups
Shared Contraindications (CI) / Precautions: People with a personal or family history of medullary thyroid cancer (MTC) or MEN2, or those with a serious allergy to the specific medication
The next step is prospective studies and clinical trials comparing patients with pretransplant diabetes on GLP-1 receptor agonists or dual agents to patients just on insulin or with any other oral medications, Campana said.