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Discuss risks and benefits with your clinician if considering any non-approved option

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While this was a relatively small, single-center study and should be interpreted with appropriate caution, it adds another encouraging signal on the potential of dorzagliatin, a global first-in-class glucokinase activator, alongside GLP-1RA therapy in obese patients with Type 2 diabetes

I tried to take 50 g of protein powder every day to limit muscle loss, but found it very difficult to stomach

Yu et al., 2012)

The only oral GLP-1 approved by the Food and Drug Administration so far is Novo Nordisk's Rybelsus, which treats Type 2 diabetes and raked in about $3.38 billion in sales in 2024