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Symptomatic patients have a waxing and waning course and may present with complaints of fatigue (75%), pruritus (25% to 70%), jaundice (30% to 69%), abdominal pain (16% to 37%), and weight loss (10% to 34%)

11 A 2023 meta-analysis of nine randomized trials confirmed that PRP significantly increases hair density at 3 and 6 months compared to placebo