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For ongoing authorization renewals, periodic BMI documentation may be required to demonstrate continued medical necessity

These microbiome changes reversed rapidly, however, when the obese mice were returned to a normal, lean diet 79

Thus, it is recommended to investigate for this AE in SGLT2i-treated patients with symptoms of ketoacidosis, such as nausea, vomiting, abdominal pain, ketonuria, and/or ketonemia, regardless of the current glucose status [74]

Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA

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Table 5 describes the comparative efficacy of HTY across disease models