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Gastrointestinal adverse events - predominantly nausea, vomiting, diarrhea, and constipation - are the most common class effects, occurring in 20%-60% of patients depending on the agent and dose, and are typically of mild-to-moderate severity, dose-dependent, and most prominent during titration

However, depression is a complex condition with multiple contributing factors, and low BDNF alone is unlikely to be the sole cause

Nov 6;159(4):70913

When researchers knock out beta-catenin signaling in mice, the animals lose the ability to generate new hair follicles entirely

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