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A phase I clinical trial of once-weekly Mazdutide (also known as IBI362 or LY3305677) with dose-escalation over 12 weeks demonstrates therapeutic efficacy in overweight and obese patients, reducing body weight by 4.8% (3 mg dosage), 6.4% (4.5 mg), and 6.0% (6 mg) [90]

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Proc Natl Acad Sci U S A 98(16):94079412

Any use outside of approved clinical trials would be outside the scope of standard clinical practice