First, a little about gut peptides Lets start at the beginning
doi: 10.1016/j.jnutbio.2013.11.009 90 AltmanBJStineZEDangCV
GIP receptors (GIPRs) are highly enriched in oligodendrocytes within the hypothalamic median eminence, and activation of these GIPRs regulates oligodendrocyte survival and myelin plasticity - this process enhances the entry of GLP-1R agonists into the brain via two key pathways: upregulating vascular endothelial growth factor A (VEGF-A) to increase blood-brain barrier permeability and facilitating GLP-1R agonist traversal of myelinated neuronal axons to target hypothalamic nuclei involved in energy homeostasis, including the ARC and PVN [81]
Peptide storage isn't magic, but it isn't casual either
Regeneracin de acil-CoA: La CPT2, en la cara matricial de la membrana interna, libera el grupo acilo del CCAT y lo transfiere a una CoA matricial, produciendo acil-CoA graso dentro de la mitocondria, listo para entrar a la beta-oxidacin
The difference is significant, especially over months of treatment
