In agreement with this, the ability of PA to protect cells against oxidative stress has been associated with inhibited ROS generation, increased GSH levels, and decreased lipid peroxidation (MDA), as shown in several studies (Lee et al., 2005
When confluent, HAECs were shifted to ALI culture with 50 L apical media for 8 days to achieve full differentiation with and without IL-13 (10 ng/mL) stimulation (R&D Systems, 213-ILB)
206 VillalbaM.BockaertJ.JournotL
Quastel JH, Stewart CP, Tunnicliffe HE
We also failed to detect an increase in MitoSOX-sensitive mitochondrial ROS production in erastin-treated RPE cells
111 As a cofactor, GSH also plays an antioxidant role through GPX4, reduces phospholipid hydroperoxide (PLOOH), peroxidized thymine, cholesterol, and fatty acids, and protects cells from oxidative damage