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Clinical trials may involve different patient populations, doses, treatment lengths, diabetes status, lifestyle support, and study designs

However, other causes of menstrual changes are completely unrelated to GLP-1s, such as perimenopause, other medications, or another health issue

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According to the ADA 2018 Guidelines [1], treatment for T2DM should start with monotherapy unless A1c is greater or equal than 9.0%, when dual therapy must be considered

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