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S5), prior reports of aberrant TNF- secretion by MBCs in patient serum correlated with negative B cell responses (Frasca et al, 2014) and support our speculation that HCMV, via gp34, may modulate non-IgG B cells in a paracrine manner to attenuate an effective humoral immunity

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doi: 10.3389/fvets.2018.00242

Miller JE, Ahn SH, Monsanto SP, Khalaj K, Koti M, Tayade C

These in vitro experiments showed that cytokines and uremic toxins reduce RBC viability and trigger eryptosis in a time- and dose-dependent manner [256]