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(2015) The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells, Cancer Lett

PTEN (phosphatase and tensin homolog deleted on chromosome 10) is a lipid phosphatase and opposes IGF-I signaling by dephosphorylating PIP3 to PIP2

After an additional twenty-four hours, cells were removed from the incubator, placed on ice, lysed (without a PBS wash) with 1 mL of ice cold 80% methanol/20% water solution containing 1.5 M metabolomics amino acid mix (Cambridge Isotope Laboratories, MSK-A2-1.2)

[DOI] [PubMed] [Google Scholar] 10.Yang Y, et al