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Furthermore, luciferase activity was significantly reduced within the 100 to +100 bp region upstream of the DEPTOR promoter, indicating the presence of an ILF3 binding site in this region (Fig
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Conclusion The regulated production of key RBC metabolites, including vasoregulatory ATP, the allosteric effector DPG, and the reductant NADPH, is sensitive to cellular cues unique to the RBC, namely its high oxidant load ( via reactive oxygen species) and its mission of efficient O 2 delivery and CO 2 clearance
Glutathione is a potent antioxidant that can help to neutralize these free radicals and reduce inflammation
