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Gut microbiota dysbiosis in AKI to CKD transition

Myofibroblasts, which are produced when HSCs are activated, deposit collagen fibers and cause liver cirrhosis (Mansour et al., 2022)

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Bmal1 deficient mice display hyperpermeability and downregulation of platelet-derived growth factor receptor (PDGFR), suggesting a significant role for Bmal1 in pericyte regulation for blood-brain barrier maintenance (Nakazato et al., 2017)