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This mechanism lets sirtuins take part in many body processes

proposed a nanocluster, which integrated catalase (CAT) with MnO 2 to realize CAT-triggered oxygen release and Mn 4+ -assisted GSH exhaustion, accompanied by abundant 1 O 2 accumulation, achieving a remarkable anticancer performance characterized by GSH depletion-improved PDT (Zhu et al., 2020)

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The gel's consistency allows for smooth application and facilitates the absorption of glutathione through the skin, directly into the systemic circulation, bypassing the gastrointestinal tract where oral glutathione may be degraded

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From the above table, it could be concluded that even though each drug is beneficial in the treatment of PDs, it also has several complications