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Patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2) should not take GLP-1 medications with the thyroid C-cell tumor boxed warning

It is frequently combined with CJC-1295 (a GHRH analogue) to study synergistic GH release through complementary GHS and GHRH receptor pathways

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