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Sturgess, J

This leads to NF-B-mediated expression of pro-inflammatory cytokines (IL-6 and TNF-), constituting a core mechanism of acute gout attacks

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A preliminary mechanistic investigation revealed that compound 16 inhibited the Akt/NF-B and MAPK signaling pathways, contributing to its anti-inflammatory effects

The company has been granted over 600 patents, both domestically and internationally, and has received two Second Class Prizes for National Science and Technology Progress, and two China Patent Gold Awards