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doi: 10.1111/imr.12971 90 ZhenGGuoQLiYWuCZhuSWangRet al
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First few months: This is typically the active titration phase - providers adjusting the dose based on tolerance and response, GI side effects (when present) often diminishing, and more visible weight changes becoming apparent for patients who respond to treatment
By identifying CSCs within a tumor, spatial transcriptomics helps identify the specialized niches they occupy and their interactions with neighboring cells
Routes of Administration Subcutaneous injection (standard): Protocols describe injection in the abdomen, thigh, or upper arm, rotating sites between injections, using standard SC technique with a 29-31 gauge insulin syringe
In addition, adipose tissue is less inflamed illustrated by lower TNF, IL-6, PAI1, and CCL7 levels (47)
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