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Estrogen regulates transcription factors STAT-1 and NF-kappB to promote inducible nitric oxide synthase and inflammatory responses

The loss of muscle mass is particularly relevant for patients with metabolic diseases and older people, for whom muscle mass loss expedites sarcopenia development

Today it is assumed that numerous diseases could be caused by epigenetic errors

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Recruitment for ME/CFS patients started just before COVID related restrictions were introduced and research was suspended: one patient and one healthy control were recruited in February 2020, others from February 2021