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This is particularly relevant for patients with pernicious anaemia, where intrinsic factor deficiency prevents adequate oral absorption

Greenberg JW, Lancaster TS, Schuessler RB, Melby SJ

Genome-wide CRISPR activation screening identified guanosine triphosphate cyclohydrolase 1 (GCH1), the rate-limiting enzyme in the synthesis of BH 4 , as a potent GPX4-independent ferroptosis-inhibiting factor

People with certain conditions, or who are pregnant or breastfeeding, should hold off, which is exactly the kind of thing we screen for before treating

Side effects consisting of headache and irritability were observed more frequently in the methylphenidate plus placebo group

There are concerns about cross-border demand, particularly from US patients seeking lower-cost alternatives