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In a double-blind, placebo-controlled study, a total of 1012 patients with mild-to-moderate hypertension received treatments of 3 combinations of amlodipine and valsartan (5 mg/80 mg, 5 mg/160 mg, 5 mg/320 mg) or amlodipine alone (5 mg), valsartan alone (80 mg, 160 mg, or 320 mg) or placebo

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