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Xavier also cautioned that these findings only serve to generate a hypothesis and that physicians should not yet recommend that patients use these drugs as replacements for traditional alternative therapies to quit smoking

The body adapts to continuous stimulation

References Pizzorno, J., 2014

This triple mechanism of action distinguishes retatrutide from existing approved therapies, which typically act on one or two of these pathways

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BMJ 347:f5934 [DOI] [PMC free article] [PubMed] [Google Scholar] 6.OBrien PE et al (2019) Long-term outcomes after bariatric surgery: a systematic review and meta-analysis of weight loss at 10 or more years for all bariatric procedures and a single-centre review of 20-year outcomes after adjustable gastric banding