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Interestingly, within this overall similarity, PD patients displayed a shift in subset composition, with classical monocytes (CD16 ) being enriched and CD16 + monocytes being reduced relative to healthy controls [22]

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For example, astrocytes express different antioxidant molecules such as glutathione peroxidase (EC 1.11.1.9), which have been inversely correlated with the severity of dopaminergic cell loss in the respective cell groups in patients with PD [4]

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