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Glucagon-receptor activity is associated with increased energy expenditure and reduced liver fat, which is the mechanistic rationale for why retatrutide produced larger weight-loss figures in early trials

Writing this down creates accountability and prevents rationalization when numbers creep upward

& Roubenoff, R

P =0.02) than treatment with other glucose-lowering therapies [98]

Avoiding an unpleasant trade-off Right now, older adults face an unpleasant trade-off: lose weight and improve your cardiovascular health, but perhaps accelerate your decline