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Upregulation of Growth Factors BPC-157 enhances the expression of several key growth factors, including: VEGF (vascular endothelial growth factor) TGF- (transforming growth factor beta) FGF (fibroblast growth factor) EGF (epidermal growth factor) These factors collectively support cellular proliferation, matrix remodeling, and tissue regeneration

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Together, the two define the standard of care that every pipeline candidate must beat, which is why so much development effort has moved toward additional receptors and easier dosing rather than incremental gains on the same mechanism

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European Journal of Pharmaceutical Sciences, October 2015, pages 7989 9