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A drug gets a black box warning when it has potentially serious adverse reactions that could lead to hospitalization and death or permanent damage

Seek same-day medical assessment if you develop unilateral leg swelling, pain, warmth, and redness (possible deep vein thrombosis), severe muscle pain with dark urine, or leg pain accompanied by fever

Several real-world cases have reported improved fertility in women taking semaglutide, even those who previously struggled to conceive

Temporary fatigue

Doctors suspect GLP-1 medicines might help fight gambling disorders Researchers say more data is needed before prescribing GLP-1 for gambling problems Health officials believe gambling problems are on the rise As gambling options become more prevalent than ever, public health experts warn that gambling addiction is rising right alongside them

Some research suggests discontinuation rates for GLP-1s may be significantly higher in the real world, particularly in people with obesity