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Preclinical studies consistently demonstrate that tinnitus models exhibit increased spontaneous excitatory postsynaptic currents (sEPSCs) and decreased spontaneous inhibitory postsynaptic currents (sIPSCs) in pyramidal neurons of the primary AC, changes that directly correlate with behavioral evidence of tinnitus (Ghimire et al., 2023)

Davis, S., Mirick, D

In NAFLD/NASH patients, the pleiotropic effects of statins are elaborated by decreased inflammation and fibrosis via modulation of cell proliferation, anti-oxidant, and anti-thrombotic activities (Chong et al., 2015)

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[DOI] [PMC free article] [PubMed] [Google Scholar] [80].Liu RM, Gaston Pravia KA