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Vitamin B12 deficiency has been linked to fatigue, tingling or loss of feeling in the extremities, irritability, memory impairment, depression, anemia, irritable bowel syndrome (IBS), constipation, poor wound healing, dry or damaged looking skin, and neurological disorders

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Hydroxocobalamin is widely recommended for the treatment of diagnosed B12 deficiency, pernicious anaemia, fatigue related to low B12, and certain neurological symptoms associated with deficiency

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