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High-throughput screening of FDA-approved drugs using oxygen biosensor plates reveals secondary mitofunctional effects

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While all Cbl initially enters the bloodstream bound to TCN2, only about 2030% of the total blood cobalamin is transported by TCN2 and is thus in the biologically active form, with the remaining 7080% bound to Hc [89]

7.6 1.1 pmol/mg protein