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I look forward to any comment or thought you may have Aaron re the bodies master anti oxidant

A tapering schedule may help a person avoid such symptoms

Evaluation of antioxidant status and oxidative stress markers in follicular fluid for human in vitro fertilization outcome

Prog Neurobiol 116:3357

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One possible explanation is that low serum vitamin B12 levels would trap folate as 5-methyltetrahydrofolate, prevent the generation of methionine from homocysteine, and therefore reduce protein synthesis and lean tissue deposition