J Clin Endocrinol Metab 99 , 33733381, (2014)
However, the high cost of these medications remains a challenge
If it persists or progresses, dose reduction or switching to a more selective anti-androgen (e.g., bicalutamide) is the next step
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Had current treatment with or history of treatment with (within 3 months prior to screening) medications that may cause significant weight gain, including, but not limited to, tricyclic antidepressants, atypical antipsychotics and mood stabilizers