protein, fiber and unsaturated fats), people with obesity typically have high rates of micronutrient deficiencies including deficiencies in vitamin A, vitamin D, vitamins B1 (thiamine) and B12 (cobalamin), folate, iron, calcium, magnesium and zinc [63,64]
We're going to get into the nuance around all of that
Meta-analyses of oral berberine trials have indicated improvements in fasting blood glucose and HbA1c levels, though study quality varied considerably
1c, 1d)
And it doesnt cause weight gain, is highly effective when taken consistently, doesnt cause hypoglycemia, and its relatively affordable. While the impact of metformin is significantly more subtle and gradual than that of GLP-1s, its still beneficial for almost anyone with diabetes, regardless of other medications
Patients with needle aversion, early need for intensification, or preference for oral therapy may benefit