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Mechanistically, this interaction is theorized to involve G-protein coupling, second messengers such as cAMP and IP3, and activation of protein kinases that regulate cellular signaling cascades

Serum estradiol level on the oocyte triggering day was measured using an ECLIA method and a commercial kit (Roche)

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A decrease in creatinine levels was noted at a higher dose of BPC 157, but not at lower doses, and animals recovered after a two-week withdrawal