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Avoid temperature excursions, since warm temperatures degrade peptides regardless of dose

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Topf MC, et al

However, the FDA black-box warning about medullary thyroid carcinoma (MTC) and thyroid C-cell hyperplasia means semaglutide is contraindicated in patients with personal or family history of MTC or multiple endocrine neoplasia syndrome type 2

Heres how they differ: 96373 Intra-arterial injection 96374 Intravenous push (not infusion) 96375 IV push with concurrent infusion 96365 Initial IV infusion, up to 1 hour Use 96372 only when no IV access is used and the administration is IM or SQ

The good news is that clinical data tells us something encouraging