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Additionally, growing awareness and updated clinical guidelines support the integration of GLP-1 drugs as frontline therapies

5.4 Hyperbaric oxygen therapy HBOT involves treatment with 100% oxygen at pressures exceeding one absolute atmosphere (ATA), enhancing oxygen delivery to tissues, reducing inflammation, and promoting healing (112, 113)

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Modulation of nitric oxide (NO) pathways via the AkteNOS axis, improving blood flow, normalizing coagulation, and protecting vascular endothelium, including prevention and reversal of thrombosis in some animal models

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