That physical expansion triggers stretch receptors and briefly elevates satiety hormones like GLP-1 and PYY
Gao L, Huang H, Zhang L, Zhang N, Fu Y, Zhu D, et al
Drugs.com, May 2026) SEMALEAN Found Function Improved Even as Lean Mass Dipped The SEMALEAN trial produced one of the more reassuring findings in this area: lean mass declined initially then stabilised , while handgrip strength improved by 4.5 kg and sarcopenic obesity prevalence fell from 49% to 33% over twelve months
Lancet (2021) 398:58398
10 in stock (can be backordered) Tirzepatide is a dual GIP/GLP-1 receptor agonist (twincretin) developed by Eli Lilly and approved by the FDA in 2022 for type 2 diabetes (Mounjaro) and in 2023 for obesity (Zepbound)
Because these medications reduce appetite and slow digestion, you naturally eat less, which makes food quality even more important