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The FDX1-mediated process culminates in profound proteotoxic stress driven by the aggregation of lipoylated mitochondrial proteins and the concomitant destabilization of Fe-S cluster proteins, which together lead to acute mitochondrial failure [3]

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Glutathiones Role in Detox & Defense During Phase I detox, your liver creates reactive compounds that can damage cells if left unchecked

2 (download XLSX Numerical data for titration experiments Source Data Fig