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Wettergren A, et al

It also plays a role in protecting B12 from being destroyed by stomach acid, such as in the stomach and intestines.[ref] TCN2 (transcobalamin II, TCN2 gene): TCN2 is a B12 transport protein that moves vitamin B12 from the bloodstream into cells throughout the body

You can take them orally or through injections

9 This is the first human study to demonstrate that a single dose of NR can cross into the brain and directly raise cerebral NAD+ levels, providing evidence that NR boosts NAD+ where it matters mostat the cellular level in the brain