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In a review of clinical trials, the combination of combined oral contraceptive pills (COCPs) with either a GLP-1RA or tirzepatide (GLP-1 and Glucose-dependent insulinotropic polypeptide (GIP) receptors agonist) did not affect the efficacy of contraceptive drugs, even though GLP-1RAs can decrease the absorption of the concomitantly administered drug through their gastric delaying effect

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"So if you have a sudden buildup of alcohol, like liquor shots, you have a higher amount that leads to more reaction and so it just takes longer to metabolize and the effect is greater." Avoid binge drinking: Binge drinking overloads the bodys ability to metabolize alcohol

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Replication with larger sample sizes with a placebo group to control for placebo effects is needed