District Judge Karen Marston has ruled that plaintiffs in the Ozempic and related GLP-1 litigation must confirm gastroparesis diagnoses with a gastric emptying study
Research published in Cell Reports Medicine in 2026 concluded directly: weight loss with GLP-1 medicines does not result in a disproportionate loss of muscle mass or function
For ethical and other reasons, I do not expect we will see randomized trials of GLP-1s during pregnancy
Maintaining Metabolic Balance Tapering doesnt just help with hunger it also helps your metabolism adjust
(Present-day weight-loss drugs work on just one or two hunger-related hormones.) One particular triple agonist, called retatrutide, has recently been shown in clinical trials to help people with severe obesity shed almost 30 percent of their body weight after about 48 weeks
These studies, conducted in cell cultures and animal models, were instrumental in demonstrating the potential for synergistic metabolic effects beyond what could be achieved with single-agonist compounds