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Since MTHFR controls the detoxification of homocysteine and the supply of methyl groups for SAM synthesis, a reduction in its activity can affect homocysteine metabolism and disturb cellular methylation processes

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The comorbidity spectrum encompasses epilepsy, anxiety, sensory abnormalities, and other multisystem disorders, necessitating comprehensive strategies targeting GABA receptors, ion channel regulation, and the gut-brain axis (100)

[2] How Does Glutathione Work

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