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About Flora Lichtman Flora Lichtman is a host of Science Friday

The major electrolytessodium, potassium, chloride, magnesium, calcium, and phosphateregulate fluid balance, maintain acid-base homeostasis, enable nerve signal transmission, facilitate muscle contraction, and support cellular metabolism

Tirzepatide (Mounjaro, Zepbound) Tirzepatide belongs to a different class of drugs called dual-action GLP-1/GIP receptor agonists

The most common electrolyte imbalances associated with GLP-1 therapy are hypokalemia (low potassium), hyponatremia (low sodium), and hypomagnesemia (low magnesium), typically resulting from gastrointestinal losses through vomiting or diarrhea combined with reduced oral intake

We do not yet have evidence that they're safe for people without obesity, diabetes, and/or cardiometabolic disease

We observed that despite both groups consuming a dose of alcohol calculated to raise blood alcohol to 0.1 g/dl (approximately 0.08 g/dl BrAC) 51,52 participants in the GLP-1RA group showed a slowed rise in BrAC and altered the subjective effects of alcohol