common glp-1 medications Part 1 of a 3-Part Series; for Weight Loss GLP-1 Agonists: A Comprehensive Overview

However, their long life-span, penetration through the bloodbrain barrier (BBB) 13 , and high therapeutic doses may allow them to directly act on central nervous system GLP-1Rs 12 , thereby causing CNS-dependent side effects

Reduced appetite and fluid intakecombined with GI symptomscan quickly lead to imbalances if not addressed early

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J Appl Physiol (1985) 1992;72:549554