4.3 GLP-1RAs and colorectal cancer He Wenjing (75) reported that GLP-1R expression was lacking in human colon cancer tissues and colon cancer cell lines
doi: 10.1161/circresaha.123.321872 48 KarwiQGLopaschukGD
Members with Kaiser's standard HMO plans can expect one of these cost-sharing scenarios after PA approval: Fixed copay plans: $75 to $150 per 28-day fill at a Kaiser pharmacy (region-dependent) Coinsurance plans: 20% to 30% of the drug cost after deductible, which on Wegovy's $1,349 monthly list price translates to $270 to $405 per month High-deductible health plans (HDHP): Full list price ($1,349/month) until the deductible is met, then coinsurance applies These numbers contrast with the out-of-pocket costs members face on more common medications
More serious adverse events, though rare, have been noted in research
Meeker JD, Barr DB, Hauser R
Muscle wasting due to amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease)
