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HIF2alpha-dependent lipid storage promotes endoplasmic reticulum homeostasis in clear-cell renal cell carcinoma

At the same time, it has a similar function to GPX7, which can increase the PDI activity of ER redox protein 1 (ERO1), promote the oxidative folding of endoplasmic reticulum proteins, and reduce oxidative stress (Raykhel et al., 2007)

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BMC Gastroenterology , 17(1), 96