can you get pregnant on a glp 1 and birth control are hearing about pregnancy risks and what has your experience been : r/glp1 So-Called “Ozempic Babies” Raise Questions

In our study, it was found that ethanol exposure resulted in significant loss of synaptic markers SYP and PSD95, as well as decrease in BDNF levels in the hippocampus of APP/PS1 mice, indicating the accumulated neural damages caused by chronic ethanol exposure at molecular level

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9 , e52473 (2020)

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Oral semaglutide versus subcutaneous liraglutide and placebo in type 2 diabetes (PIONEER 4)

Key Highlights Orforglipron (Eli Lilly) * 13.6% weight loss in Phase 2 * 2.1% HbA1c reduction * Highest efficacy among the three molecules in Phase 2 * Subsequently confirmed efficacy in Phase 3 with up to 14.7% weight loss * First and only FDA-approved oral small-molecule GLP-1 receptor agonist (Foundayo) Elecoglipron (AstraZeneca) * 11.8% weight loss * 1.9% HbA1c reduction * Strong Phase 2b results * Currently advancing into a global Phase 3 program Aleniglipron (Structure Therapeutics) * 12.1% weight loss * 1.5% HbA1c reduction * Encouraging efficacy with ongoing Phase 3 development Phase 2 Efficacy Comparison Weight Loss * Orforglipron: 13.6% * Aleniglipron: 12.1% * Elecoglipron: 11.8% HbA1c Reduction * Orforglipron: 2.1% * Elecoglipron: 1.9% * Aleniglipron: 1.5% As Structure Therapeutics expanded their testing into the ACCESS II trial and evaluated higher doses (specifically escalation protocols reaching 180 mg and 240 mg), the efficacy numbers jumped significantly