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Acetaminophen potently inhibits COX-3, and this finding likely explains the reason that acetaminophen has little anti-inflammatory action

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TB-500 has a longer plasma half-life of approximately 2-3 hours due to its larger molecular size (~4963 g/mol) and slower clearance

Carmot Therapeutics is a U.S.-based biotech company focused on developing incretin-based therapies, including CT-388 (a weekly injectable dual GLP-1/GIP agonist), an oral small-molecule GLP-1 agonist (CT-996), and another injectable GLP-1/GIP candidate (CT-868)