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However, only the animals that were administered with the incretin-based compounds (GLP-1 and GLP-1MK-801) displayed increased baseline-corrected glucose-stimulated insulin secretion (Extended Data Fig

A 20mg vial holds ~5 weeks of supply at 4mg/week, but reconstituted retatrutide is generally only stable ~2830 days

Available dosing information comes from experimental and preclinical studies rather than standardized laboratory protocols

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