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Zhao F, Zhou Q, Cong Z, et al
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GIP receptor activation in the context of GLP-1 co-agonism appears to enhance weight loss beyond what GLP-1 activation alone achieves
Given the rapid degradation of the natural GLP-1 hormone (with a half-life of only 2 min), with therapeutic potential motivated the development of long-acting GLP-1 receptor agonists (GLP-1 RAs)
Heres more about why we made the change
These are synthetic versions of the GLP-1 hormone designed to last much longer
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