HUVECs (310 4 cells per well) were seeded in top chambers with DMSO or various doses of BPC-157 (1 g/mL, 5 g/mL, and 10 g/mL) in 500 mL RPMI 1640 with 0.5% FBS
Acknowledgements We thank Davide Chiarugi and Katherine Lawler for their discussions and advice that helped shape this work
Schedule follow-up to monitor for post-operative side effects or complications Schedule early outpatient or virtual visit 3 to 7 days of restart to monitor for GI symptoms, hypoglycemia if used in combination with other glucose-lowering agents, wound concerns, or infection
We provide follow-up, dose adjustment, and lab monitoring under doctor supervision
The cessation of GLP-1 RA treatment can lead to weight gain and hyperglycemia
Why this is interesting for sports and weight loss The practical consequences of this mechanism are twofold: For the athlete : better utilization of fats as fuel during exercise, which allows for preserving muscle glycogen and delaying fatigue